摘要
目的分析丘脑底核-脑深部电刺激术(STN-DBS)治疗帕金森病的术后程控参数及效果,为帕金森病STN-DBS术后程控及术后管理提供参考。方法纳入2012~2018年就诊于新疆医科大学第一附属医院87例患者,应用UPDRS-Ⅲ评分UPDRS-II日常生活活动评分UPDRS-I精神行为情绪评分量表MMSE简易精神量表PDQ-39生活质量评分量表分析手术前后帕金森病患者运动及非运动症状改善情况,评估程控参数的设置对帕金森病人症状改善及生活质量改善作用。结果帕金森病患者与术前相比,患者术后UPDRSⅠ评分UPDRSⅠⅡ评分UPDRSⅢ评分UPDRSⅣ评分改善明显,手术后随访至今,患者症状改善稳定,生活质量明显提高。结论STN-DBS是一种安全,有效治疗帕金森病的方法,并减少药物的剂量及药物所致副作用,术后程控是脑深部电极植入器治疗的重要一环。
Objective To analyze the postoperative program-controlled parameters to the improvement and evaluate the effects of subthalamus-deep brain stimulation(STN-DBS)for the treatment of Parkinson’s disease.Methods 87 patients admitted to the study from 2016 to2018,applying UPDRS in the improvement of movement and non-movement symptoms in patients with Parkinson’s disease before and after surgery and evaluate the effects of programmed parameters.Results Compared with preoperative patients UPDRS score improved significantly,follow-up after surgery,patients improve stability,quality of life has improved significantly.Conclusion STN-DBS is a safe and effective method for the treatment of Parkinson’s disease,and Postoperative program control is an important part of the treatment.
作者
陆敬潮
冯兆海
石鑫
姜磊
郝玉军
Lu Jingchao;Feng Zhaohai;ShiXin(Department of Neurosurgery,the First Affiliale Hospital of Xinjiang Medical University,Urumqi,830054,China)
出处
《立体定向和功能性神经外科杂志》
2019年第1期9-12,共4页
Chinese Journal of Stereotactic and Functional Neurosurgery
关键词
帕金森病
丘脑底核
脑深部电刺激术
程控
Parkinson’s disease,PD
Subthalamic nucleus,STN
Deep brain stimulation
program control
