内蒙古医科大学附属医院47年浅部真菌病及病原菌分析

Analysis of superficial mycosis and pathogenic fungi in affiliated hospital of Inner Mongolia Medical University in the past 47 years

目的探讨内蒙古医科大学附属医院近50年浅部真菌病分布以及致病菌种构成的动态变化。方法对该院皮肤性病科47年真菌培养阳性的15648例患者临床资料、真菌培养鉴定结果进行分析。结果浅部真菌病位列前3的是足癣、手癣和甲真菌病:甲真菌病病原菌以红色毛癣菌为主,白念珠菌和其他酵母菌随着年代的增加逐渐增多;体癣与头癣病原菌以犬小孢子菌为主,并随着年代逐渐增多;所有培养阳性菌株中,列前3位的是红色毛癣菌、须癣毛癣菌复合体和犬小孢子菌。结论从1970—2016年浅部真菌病的病原菌变化不大,皮肤癣菌仍占主要优势,以红色毛癣菌、须癣毛癣菌复合体为主。

Objective To understand the distribution of superficial mycosis and dynamic changes of pathogenic fungi in the last 50 years. Methods The clinical data and pathogenic species of 15648 patients who tested positive for fungi from Department of Dermatology,Affiliated Hospital of Inner Mongolia Medical University in the past 47 years were retrospectively analyzed. Result The top three of the superficial mycosis were tinea pedis, tinea manuum, and onychomycosis; in onychomycosis, Trichophyton rubrum was the most frequent pathogen,meanwhile Candida and other microzyme increased over time; in tinea corporis and tinea capitis, Microsporum canis was the most commom pathogen and increased over time; of all the samples, the top 3 pathogenic fungi were Trichophyton rubrum, Trichophyton mentagrophytes and Microsporoum canis. Conclusion The overall trend of the pathogenic fungi of superficial mycosis is similar to that in other domestic regions.