气管和支气管乳头状瘤临床分析

Clinical analysis of tracheal and bronchial papillomatosis

目的总结气管和支气管乳头状瘤的临床特点及支气管镜下介入治疗情况。方法回顾性分析2012年1月-2018年6月在应急总医院确诊的气管和支气管乳头状瘤的24例患者临床资料,进行分析、总结。16例患者有吸烟史,其中男患者13例;19例良性,5例恶变;9例病变为单发,占37.5%,累及2个及2个以上部位的共15例,占62.5%。喉部受累4例,中央型气道受累21例,二级支气管受累3例。肿瘤可以侵犯多个部位。结果经支气管镜下介入治疗后,气道狭窄程度、气促分级、卡氏评分(KPS)均得到明显改善(P<0.01)。结论气管和支气管乳头状瘤是气道内少见的肿瘤,多为良性病变,可以发生恶变,支气管镜下介入治疗是有效的治疗手段。

Objective To summarize the clinical characteristics and interventional treatment of tracheobronchial papillomatosis.Methods Clinical data of 24 patients with tracheobronchial papillomatosis from January 2012 to June 2018 were retrospectively analyzed.16 patients had a history of smoking and 13 of them were men.19 cases were benign and 5 were malignant change.9 cases were solitary,accounting for 37.5%,involving 2 and more than 2 parts,accounting for 62.5%.Laryngeal involvement was found in 4 cases.Central airway were involved in 21 cases,and secondary bronchial involvement in 3 cases.Tumors can encroach on multiple sites.Results After tracheal interventional therapy,airway stenosis degree,dyspnea grade and KPS score were significantly improved(P<0.01).Conclusion Tracheal and bronchial papillomatosis is a rare tumor in the airway,most of which are benign,while may have malignant change.Therapeutic bronchoscopy intervention is an effective treatment.