云南省石屏县汉族彝族外阴阴道念珠菌病危险因素分析

Analysis of the risk factors of vulvovaginal candidiasis in the Han Nationality and Yi Nationality in Shiping prefecture of Yunnan province

目的探讨外阴阴道念珠菌病发病的危险因素。方法使用专门设计的调查表在云南省石屏县彝族聚居的2个县级医院共调查234例外阴阴道念珠菌病患者(汉族和彝族)和226例健康女性对照者(汉族和彝族),使用单因素分析和多因素Logistic回归分析,并探讨不同民族间发生外阴阴道念珠菌病危险因素有无差异。结果患者组与健康组比较:性伴患病、经期性生活、口服避孕药、人流史、合并其他性病、口服抗生素、心情抑郁、阴道冲洗、穿紧身衣、宫内节育器为其危险因素。汉族患者与彝族患者比较,口服避孕药、口服抗生素、心情抑郁是导致外阴阴道念珠菌病的危险因素。汉族外阴阴道念珠菌病发生的危险因素包括:口服避孕药、口服抗生素、心情抑郁等。彝族外阴阴道念珠菌病发生的危险因素包括:经期性生活、宫内节育器、阴道冲洗等。结论性伴患病、经期性生活、口服避孕药、人流史是导致外阴阴道念珠菌病发病的主要危险因素。相对彝族群体而言,口服避孕药、口服抗生素、心情抑郁是导致汉族群体发生外阴阴道念珠菌病的危险因素。

Objective To investigate the risk factors for the pathogenesis of vulvovaginal candidiasis.Methods Using“vulvovaginal candidiasis epidemiology survey”in 2 county hospitals to execute investigation,which include 234 cases of vulvovaginal candidiasis patients(Han and Yi Nationality),and control were 226 healthy women(Han and Yi Nationality).Using single factor analysis and multiple factor Logistic regression,to investigate the risk factors of vulvovaginal candidiasis in this area,further explore differences between Han nationality and Yi nationality.Results(1)Single factor analysis indicated that sexual partner with vulvovaginal candidiasis,engaging in sexual activity during menstruation,oral contraceptives,a history of induced abortion,being accompanied by other STDs,oral antibiotics,depression,vaginal douching,wearing tight clothes and Intrauterine device are the risk factors for patient group.(2)Compared with the Yi Nationality patients,the oral contraceptives,oral antibiotics and depression are the risk factors for Han Nationality patients.Conclusion Compared with the health group,the risk factors of sexual partners,menstrual life,oral contraceptives,the history of human flow,and other factors are the risk factors for patient group.Compared with the Yi Nationality patients,the oral contraceptives,oral antibiotics and depression are the risk factors for Han Nationality patients.