带状疱疹后遗神经痛的影响因素及其对策分析

Influencing factors and countermeasures of postherpetic neuralgia

目的探讨带状疱疹后遗神经痛的影响因素及其对策。方法选取2015年12月至2017年12月某医院带状疱疹患者546例,收集患者的临床资料,分析带状疱疹发生后遗神经痛的影响因素。结果546例带状疱疹患者中,发生后遗神经痛有120例、发生率为21.98%;单因素分析结果显示,性别、年龄、合并糖尿病、带状疱疹分型、皮损面积、前驱痛、急性期疼痛程度、初始治疗时间与带状疱疹发生后遗神经痛有关(P<0.05);Logistic多因素分析显示,年龄>50岁、合并糖尿病、皮损面积>5%、前驱痛、初始治疗时间<3 d是带状疱疹发生后遗神经痛的独立危险因素(P<0.05)。结论带状疱疹发生后遗神经痛的风险高,且其与多因素有关,尤其是应加强对年龄>50岁、合并糖尿病、皮损面积>5%、前驱痛、初始治疗时间<3 d等患者的干预。

Objective To discuss the influencing factors and countermeasures of postherpetic neuralgia.Methods Totally 546 patients with herpes zoster were selected in our Hospital from December 2015 to December 2017.The clinical data of patients were collected,the influencing factors of postherpetic neuralgia occurrence in herpes zoster was investigated,and its countermeasures was analyzed.Results Of the 546 herpes zoster patients,120 patients had postherpetic neuralgia and the incidence was 21.98%.Univariate analysis showed that,age,sex,diabetes mellitus,herpes zoster typing,lesion area,prodromal pain,acute pain degree and initial treatment time were associated with postherpetic neuralgia in herpes zoster(P<0.05).Logistic multivariate analysis showed that,aged over 50 years old,diabetes mellitus,lesion area over 5%,prodromal pain and initial treatment time less than 3 days were the independent risk factors for postherpetic neuralgia in herpes zoster(P<0.05).Conclusion The risk of postherpetic neuralgia in herpes zoster is high,and it is related to many factors.In particular,the intervention should be strengthened in patients over 50 years old,with diabetes mellitus,skin lesion area over 5%,prodromal pain,and initial treatment time less than 3 days,etc.