丁酸钠对犊牛胃肠道发育的研究进展

Research Progress on the Effect of Sodium Butyrate on the Development of Gastrointestinal Tract of Calves

丁酸钠是一种绿色新型饲料添加剂,目前在动物饲料中应用广泛,且效果良好。作者主要介绍了丁酸钠的生物学功能、对犊牛胃肠道发育的影响及其在犊牛日粮中的应用效果。重点总结了丁酸钠促进犊牛胃肠道发育的影响机制,包括作为胃肠道组织的能量来源调控激素和生长因子的分泌,提高消化和吸收相关酶的分泌及活性,提高肠道免疫细胞保护性蛋白的分泌等。现有研究表明,日粮干物质中添加0.3%丁酸钠就能达到促进犊牛生长和胃肠道发育的效果,但具体添加水平、添加阶段和方式等尚不明确。此外,日粮粗饲料水平、精料发酵所产生的内源丁酸对外源丁酸钠的作用效果是否有影响也鲜有报道,有待进一步开展研究。

Sodium butyrate is a new feed additive which is widely used in animal feed,and its effects is reported to be positive in many literatures.This paper mainly introduces the biological function of sodium butyrate,its effect on development of calves’gastrointestinal tract and the effects of being used as calves’feed additive.The authors mainly reviewed the mechanism of sodium butyrate promoting the development of gastrointestinal tract,including being used as energy source of gastrointestinal tract of animal,regulating secretion of hormones and growth factor,improving secretion and activity of digesting and absorption related enzymes,and increasing secretion of protective proteins of intestinal immune cells,etc.The present studies showed that addition of 0.3%sodium butyrate into feed dry matter could promote the development of gastrointestinal tract and growth of calves,but the addition level,phase and way were need to be further researched.Besides,there is few report on the influences of dietary forage level and endogenous butyrate which produced by concentrate fermentation on function of exogenous butyrate,which need to be further researched.