医院耐碳青霉烯类肺炎克雷伯菌38例分析

Clinical investigation and analysis of carbapenem-resistant klebsiella pneumonia

目的分析医院耐碳青霉烯类肺炎克雷伯菌(CRKP)的分布特征和耐药情况,为临床抗菌药物合理使用预防和感染控制管理提供依据。方法收集2017年1月至2017年12月皖北煤电集团总医院临床标本分离的38株CRKP,通过回顾性调查、同源性分析,运用Excel2007软件进行统计分析。结果仅有5株在3月内未入住过重症医学科,占13.16%,其余33株均与重症医学科有关,占86.84%。住院时间长、手术、病情危重、气管插管、抗菌药物使用时间长、抗菌药物使用种类均为危险因素。结论重症医学科应针对其可能的危险因素,加强操作过程管理、规范抗菌药物临床使用、强化医院感染监测等方法,来预防与减少CRKP感染发生。

Objective To understand the distribution and drug resistance of carbapenem?resistant Klebsiella pneumoniae(CRKP)in the General Hospital of Northern Anhui Coal and Electricity Group,and to provide evidence for the rational use of antibiotics,prevention and infection control.Methods 38 strains of carbapenem?resistant Klebsiella pneumoniae isolated from clinical speci?mens from January 2017 to December 2017 were retrospectively investigated and analyzed by Excel 2007 software.Results Only 5 strains had not been admitted to ICM within 3 months,accounting for 13.16%.The remaining 33 strains were related to ICM,ac?counting for 86.84%.Long hospitalization time,operation,critical illness,tracheal intubation,long use of antibiotics and types of anti?biotics were risk factors.Conclusion The critical care department should strengthen the management of operation process,stan?dardize the clinical use of antibiotics and strengthen the monitoring of nosocomial infection in order to prevent and reduce the inci?dence of CRKP infection in view of its possible risk factors.