视神经损伤后视觉功能重塑的研究进展

Research progress of visual function remodeling after optic nerve injury

青光眼或其他原因导致的视神经损伤,以及颅脑损伤导致的视觉损伤通常被认为是不可逆的。然而,近年来的研究发现,神经系统具有明显的神经可塑性(neuroplasticity)。人们尝试对神经的可塑性作用机制进行阐明,并通过视觉经验、电流刺激、代偿性眼球运动训练及压力疏导等方法来激活或活化“休眠”细胞及视觉传递,并构建自组织映射模型对视觉重塑效果进行预估。

Optic neuron injury caused by glaucoma and other factors commonly considered as irreversible.However,some evidences demonstrate considerable neuroplasticity in the nervous system.In this review,we try to illuminate the mechanism of neuroplasticity,and reactivate the“silent”cell and neural transmission visual experience,alternating current stimulation,eye yoga,and anti-stress program,and so on.Predict visual change after intervention using self-organizing maps.