鼻腔泪囊吻合术中填充美乐胶治疗小泪囊泪囊炎

Clinical efficacy of MeroGel in the treatment of dacryocystitis with small dacryocyst

目的:观察美乐胶(MeroGel)在经鼻内镜下鼻腔泪囊吻合术(EN-DCR)治疗小泪囊泪囊炎的疗效。方法:选取2014-06/2018-12我院收治的小泪囊泪囊炎患者185例185眼,鼻腔泪囊吻合术(DCR)中分别使用MeroGel、明胶海绵、膨胀海绵和凡士林纱条,观察各组患者术后并发症和造口恢复情况。结果:使用MeroGel的患者术后眼角和鼻腔渗血少,后期复查无痛苦,造口恢复情况较其他各组更佳(P<0.05)。结论:MeroGel减少了DCR术后渗血,同时其可降解性有助于EN-DCR术后造口黏膜上皮化,尤其在小泪囊泪囊炎术后,能抑制造口粘连及周边肉芽组织增生,大大提高小泪囊泪囊炎的成功率,相比于其他填塞材料,使用MeroGel后并发症更少,患者更舒适。

AIM:To observe the efficacy of MeroGel in the treatment of dacryocystitis with small dacryocyst by transnasal endoscope dacryocystorhinostomy.METHODS:Totally 185 cases(185 eyes)of dacryocystitis with small dacryocyst were admitted in Hankou Aier Eye Hospital from June 2014 to December 2018.MeroGel,gelatin sponge,expansive sponge and vaseline gauze were used during the dacryocystorhinostomy.Complications and recoveries were observed.RESULTS:Less bleeding and painless in patients who used MeroGel,and the anastomotic stoma was better than other groups,the difference was statistically significant(P<0.05).CONCLUSION:The hemostasis effect of MeroGel reduced the bleeding after DCR.At the same time,its degradability is conducive to the epithelialization of the anastomotic stoma after EN-DCR,especially after the surgery with dacryocystitis with small dacryocyst.It can inhibit the adhesion of anastomotic stoma and the peripheral granulation tissue proliferation.The success rate of dacryocystitis with small dacryocyst was improved greatly.Compared with other filling materials,there were fewer complications and more comfortable patients after using MeroGel.