天然物质抗幽门螺杆菌黏附的研究进展

Development on inhibition of H. pylori adhesion by natural substances

幽门螺杆菌(H. pylori)是胃内一种长期慢性感染性致病菌,近年来,H. pylori的耐药性问题引发人们寻找新的补充替代药物。H. pylori对胃黏膜的黏附是其致病的先决条件,抑制H. pylori黏附或使H. pylori脱黏附,就能预防或消除由于H. pylori感染引起的危害。文章简要地介绍H. pylori的黏附机制,并对近几年国内外研究者利用天然物质抑制H. pylori黏附的研究进行概述,旨在为研究和开发H. pylori新的治疗方法提供理论参考。

H.pylori is a long-term chronic infectious pathogen in the stomach.In recent years,the antibiotic resistance of H.pylori has caused people to seek new supplemental alternative drugs.The adhesion of H.pylori to gastric mucosa is a prerequisite for its pathogenesis.Inhibition of H.pylori adhesion can prevent or eliminate the harm caused by H.pylori infection.This article briefly introduces the adhesion mechanism of H.pylori,and summarizes the studies on the inhibition of H.pylori adhesion by natural substances in recent years,aiming to provide a theoretical reference for the new treatments of H.pylori.