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容积旋转调强放疗治疗局部晚期非小细胞肺癌的临床效果 被引量:11

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摘要 目的研究容积旋转调强放疗(VMAT)治疗局部晚期非小细胞肺癌近期疗效及急性放射性损伤发生情况。方法选取2016年1月至2017年8月六安市中医院肿瘤放疗科收治的50例ⅢA~ⅢB期局部晚期非小细胞肺癌患者,采用随机数字表法分为VMAT组和静态适形调强(IMRT)组,每组25例。分别接受VMAT和IMRT治疗,并同步给予足叶乙苷+顺铂方案化疗。随访至放化疗结束后1个月,观察两组患者近期疗效及放疗并发症情况。结果VMAT组和IMRT组患者疾病控制率分别为92%和88%,差异无统计学意义(P>0.05);VMAT组和IMRT组放射性肺炎、放射性食管炎、放射性心脏损害发生率分别为32%、40%、8%、56%和76%、32%、4%、52%,其中VMAT组放射性肺炎发生率低于IMRT组,差异有统计学意义(P<0.05)。结论VMRT技术在临床疗效方面并不优于IMRT,但其可能一定程度降低了放射性肺炎发生率。
出处 《安徽医学》 2019年第8期889-891,共3页 Anhui Medical Journal
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