河北省免费孕前优生健康检查中梅毒抗体阳性者随访调查分析

Investigation of people with syphilis positive from the national free pre pregnancy health examination project in Hebei province

目的:了解国家免费孕前优生健康检查中梅毒螺旋体血清抗体阳性者诊治情况和妊娠结局。方法:根据河北省孕前优生数据库资料,将2015—2016年免费孕前优生健康检查中梅毒初筛≥5例阳性的县级机构纳入随访范围,采用自制的调查表对梅毒初筛阳性者诊治情况和生育结局进行随访。结果:纳入调查的19个县级妇幼保健计划生育技术服务机构共计梅毒螺旋体血清抗体阳性490例,确证试验阳性326例(66.5%),其中女方197例(60.4%),男方129例(39.6%);新出生胎儿208例中207例(99.5%)梅毒抗体阴性,1例阳性(0.5%)。结论:国家免费孕前优生健康检查,可以在夫妇备孕前有效发现梅毒感染者,进行针对性的指导和治疗,对避免孕期梅毒感染,减少母婴传播具有重要意义。

Objective:To evaluate the situation of diagnosis and treatment and pregnancy outcomes of people with syphilis positive from the national free pre pregnancy health examination project.Methods:The county service centers with five or more people with syphilis positive from the national free pre pregnancy health examination project from 2015 to 2016 were included in this study.The self designed questionnaire was used to follow up the situation of diagnosis and treatment and pregnancy outcomes of people with positive syphilis.Results:There were 490 people with syphilis positive in 19 included county service centers,and 326(66.5%)people were confirmed syphilis positive,which included 197(60.4%)man and 129(39.6%)women.In the 208 newborns,207(99.5%)were syphilis negative and 1(0.5%)was syphilis positive.Conclusion:The couples with syphilis infections can be found effectively by the national free pre pregnancy health examination,and the people with syphilis positive after the national free pre pregnancy health examination should be accepted further guidance and treatment for avoiding syphilis infection during pregnancy and reducing mother to child transmission.