摘要
细菌源性的尿毒症毒素是慢性肾脏病(Chronic Kidney Disease,CKD)快速进展的高危因素,肠道菌群失调后加剧尿毒素蓄积并诱发全身性微炎症反应,从而导致肾脏损伤,因此从调节肠道菌群、改变细菌代谢的角度来干预慢性肾脏病可能是一个新的治疗靶点,目前各种调节肠道菌群及减少尿毒素吸收的微生态制剂已广泛应用于临床。
Bacterial-derived uremic toxin is a high-risk factor for the rapid progression of chronic kidney disease.After intestinal flora imbalance,it exacerbates urinary toxin accumulation and induces systemic microinflammation,which leads to kidney damage.Intervention of chronic kidney disease from the perspective of regulating intestinal flora and changing bacterial metabolism may be a new therapeutic target.Currently,various microecological preparations for regulating intestinal flora and reducing absorption of urinary toxin have been widely used in clinical practice.
出处
《中医临床研究》
2019年第20期9-11,共3页
Clinical Journal Of Chinese Medicine
关键词
肠道微生态
慢性肾脏病
微生态制剂
Intestinal micro-ecology
Chronic kidney disease
Microecological preparation
