癫痫共病抑郁的机制及临床诊疗

Research of the mechanism and clinical diagnosis and treatment of comorbid epilepsy and depression

本文目的是探讨癫痫共病抑郁的可能机制及临床诊疗。癫痫是一种常见的、慢性的、致残性的神经疾病,癫痫患者生活质量下降,存在明显的负性情绪,常伴发各种精神疾病。癫痫与抑郁具有共同的神经生物学基础,可能存在共同的发病机制。本文从癫痫共病抑郁的发病机制、临床诊断及治疗方面予以总结归纳。

The purpose of this article was to explore the possible mechanism and clinical diagnosis and treatment of comorbidity of epilepsy and depression.Epilepsy is a common,chronic and disabled neurological disease.The quality of life of epilepsy patients is poor due to high psychological stress and various mental disorder complications.Epilepsy and depression share a common neurobiological basis,suggesting that there may be a common pathogenesis,so this article mainly summarizes the pathogenesis,clinical diagnosis and treatment of comorbid epilepsy and depression.