高效保湿霜的制备及保湿性能研究

Study on preparation and moisture performance of highly effective moisturizing cream

选择神经酰胺作为保湿剂,以165单甘脂和MONTANOV 68为复合乳化剂、S-305为助乳化剂,制备一款具有高效保湿效果的保湿霜.通过正交试验对乳化体系中乳化剂的用量和配比进行选择,并对保湿霜的稳定性和使用效果进行评价.结果表明:当复合乳化剂用量为5%,165单甘脂与MONTANOV 68的质量比为2 GA6FA 1,S-305的质量分数为0.6%时,所得保湿霜稳定性最好.在恒温恒湿的环境下,当神经酰胺加入量为2.5%时,保湿霜具有很好的保湿效果,在涂抹15 min后,皮肤水分增长率为74.47%,在120 min内皮肤水分增长率保持在50%以上.与两种市售产品相比,该方法所选最佳配方制得的保湿霜在吸收效果、涂展性、滋润效果、细腻感等方面均有较好的效果,其总评效果与市售产品一致.

Choosing ceramide as a moisturizer,using 165 monoglyceride and MONTANOV 68 as a composite emulsifier and S-305 as a co-emulsifier,a moisturizing cream with high moisturizing effect was prepared.The amount and proportion of the emulsifier in the emulsion system were selected by orthogonal test,and the stability and using effect of the moisturizing cream were evaluated.The results showed that when the dosage of composite emulsifier was 5%,the mass ratio of 165 monoglyceride to MONTANOV 68 was 2 GA6FA 1,and the mass fraction of S-305 was 0.6%,the obtained moisturizing cream had the best stability;In the environment of constant temperature and humidity,when the amount of ceramide added was 2.5%,the moisturizing cream had a good moisturizing effect.After 15 minutes of application,the skin moisture growth rate was 74.47%,and the skin moisture growth rate remained above 50%in 120 minutes.Compared with the two products sold in the market,the moisturizing cream which made from the best formula selected by this method had a good effect in terms of absorption effect,spreadability,moisturizing effect,and delicate feeling,and the overall evaluation effect was consistent with the commercially available product.