光动力治疗宫颈高危型人乳头状瘤病毒感染性疾病的疗效及护理

The 5-aminolevulinic acid photodynamic therapy in the treatment of high-risk human papillomavirus infection and related nursing management

目的观察外用盐酸氨酮戊酸散光动力疗法(ALA-PDT)在治疗高危型人乳头状瘤病毒(HPV)持续性感染中的有效性,总结护理措施。方法选取高危型HPV感染时间>12个月的25例患者,根据宫颈解剖结构特点选择宫颈上药方式,并在治疗的不同阶段实施护理干预。治疗后4周观察HPV的转阴率及不良反应。结果25例患者均完成治疗,累积阴转率为84.00%(21/25)。结论ALA-PDT是一种安全、有效的高危型HPV持续性感染的治疗方法。在治疗过程中应开展综合护理措施和人文关怀,改善患者负性情绪。

Objective To observe the effect of 5-aminolevulinic acid photodynamic therapy(ALA-PDT)in the treatment of high-risk human papillomavirus(HR-HPV)infection,and summarize related nursing interventions during the treatment.Methods Totally 25 patients with HR-HPV positive for more than 12 months were included in this study.The 5-aminolevulinic acid was used according to the anatomical features of cervix uteri.The comprehensive nursing was carried out during the period of ALA-PDT.The rate of negative conversion of HPV and adverse reaction were observed at 4 weeks after treatment.Results All 25 patients completed the trail of ALA-PDT.The cumulative negative conversion rate was 84.00%(21/25).Conclusion The ALA-PDT is a safe and effective treatment for HR-HPV infection.It is also required to carry out comprehensive nursing interventions and humanistic care during the treatment,in order to relieve the negative emotion of patients.