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IL-6 IL-2和IL-10在老年髋部手术后认知障碍机制中的作用探讨 被引量:2

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摘要 目的探析老年髋部手术后认知障碍患者外周静脉血中的IL-6、IL-2及IL-10水平情况。方法回顾性分析2018年3月—2019年2月期间来我院接受髋部全麻手术治疗的40例老年患者,根据患者术后是否发生认知障碍(POCD)症状分成2组,20例非POCD患者设为对照组,20例POCD患者设为观察组,比较分析2组术前1 h、术后2 h外周静脉血中IL-6、IL-2及IL-10水平情况。结果术后观察组外周静脉血中IL-6、IL-2、IL-10升高,与对照组相比,差异均有统计学意义(P<0.05)。结论老年髋部术后认知障碍患者血清中IL-6、IL-2、IL-10等炎症因子有明显增高,其与POCD的发生具有密切联系。
出处 《基层医学论坛》 2019年第29期4209-4210,共2页 The Medical Forum
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