腹部及阴道彩超对孕早期胎儿畸形诊断效能的影响

Effect of Abdominal and Vaginal Color Doppler Ultrasound on the Diagnostic Efficiency of Fetal Malformation in Early Pregnancy

目的:探究腹部及阴道彩超对孕早期胎儿畸形诊断效能的影响。方法:选取我院2016年1月~2017年12月行胎儿畸形筛查的妊娠早期孕妇550例,均行腹部、阴道彩超检查。对比腹部彩超检查、阴道彩超检查及联合检查敏感度、特异度、准确度。结果:随访结果:8例双胎均正常,19例单胎异常,523例单胎正常,胎儿畸形共19例(3.45%);联合检查敏感度94.74%(18/19),特异度99.62%(529/531),准确度99.45%(547/550)高于腹部彩超检查、阴道彩超检查敏感度[73.68%(14/19)、78.95%(15/19)]、特异度[98.31%(522/531)、99.62%(529/531)]、准确度[97.45%(536/550)、98.00%(539/550)]。结论:腹部及阴道彩超联合应用于孕早期胎儿畸形诊断,可提高诊断敏感度、特异度、准确度,为早期畸形胎儿合理干预提供依据。

Objective:To investigate the effect of abdominal and vaginal color Doppler ultrasound on the diagnostic efficacy of fetal malformation in early pregnancy.Methods:550 pregnant women who underwent fetal malformation screening in our hospital from January 2016 to December 2017 were selected.Both abdominal and vaginal ultrasound examinations were performed.Compare the sensitivity,specificity and accuracy of abdominal ultrasonography,vaginal ultrasonography and joint examination.Results:Follow-up results:8 cases of twins were normal,19 cases of single-fetal abnormalities,523 cases of single-fetal normal,fetal abnormalities in 19 cases(3.45%);The sensitivity,specificity and accuracy of combined examination were 94.74%(18/19),99.62%(529/531)and 99.45%(547/550)higher than those of abdominal color Doppler ultrasonography,vaginal color Doppler ultrasonography[73.68%(14/19),78.95%(15/19)],specificity[98.31%(522/531),99.62%(529/531)],accuracy[97.45%(536/550),98.00%(539/550)].Conclusion:The combination of abdominal and vaginal color Doppler ultrasound in the diagnosis of fetal malformation in early pregnancy can improve the sensitivity,specificity and accuracy of diagnosis,and provide a basis for reasonable intervention of early malformation fetus.