长正五聚蛋白3在动脉粥样硬化和心血管疾病中作用研究的新进展

Research Progress of Pentapycin 3 in Atherosclerosis and Cardiovascular Diseases

长正五聚蛋白3是一种急相期反应蛋白,最近证实在心血管疾病的多方面发挥作用。长正五聚蛋白3参与炎症反应、血管生成和血管组织重塑,进而在动脉粥样硬化斑块的形成和稳定、心肌梗死的发病率及心力衰竭的预后等多方面作用。现就长正五聚蛋白3在动脉粥样硬化及心血管疾病中的研究进展进行综述。

Pentraxin 3 is an acute phase reactive protein,which has recently been proved to play a multifaceted role in atherosclerosis.Pentraxin 3 is involved in inflammation,angiogenesis and vascular tissue remodeling,and then plays a multifaceted role in the formation and stability of atherosclerotic plaques,the incidence of myocardial infarction and the prognosis of heart failure.This article reviews the research progress of pentraxin 3 in atherosclerosis and cardiovascular diseases.