脑室外引流术后继发颅内感染的多因素分析

Risk factors of intracranial infection after extraventricular drainage by Logistic regression

目的研究脑室出血外引流术后继发颅内感染的危险因素,为预防和治疗提供依据。方法回顾性分析352例脑室出血外引流患者,采用Logistic回归分析筛选出术后并发颅内感染的危险因素。结果352例患者发生术后颅内感染30例,分析显示,应用尿激酶灌注、脑脊液取样、置管时间>7 d、双侧脑室外置管、未应用皮下隧道是脑室外引流发生术后颅内感染的独立危险因素。结论应用皮下隧道可减少术后颅内感染的发生,双侧脑室外引流较单侧脑室外引流发生术后颅内发感染的概率高。应用尿激酶灌注、脑脊液取样、长时间置管都会增加术后发生颅内感染的概率。

Objective To study the risk factors of intracranial infection after extraventricular drainage in ventricular hemorrhage,and to provide evidence for prevention and treatment.Methods A retrospective analysis of 352 patients with extraventricular hemorrhage was performed.Logistic regression analysis was used to screen out the risk factors for postoperative intracranial infection.Results Thirty patients with postoperative intracranial infection occurred in 352 patients.The analysis showed that the application of urokinase perfusion,cerebrospinal fluid sampling,time tube placement>7 days,bilateral cerebral external catheterization,and no subcutaneous tunnel were used for extracranial drainage.Independent risk factors for internal infections.Conclusion The application of subcutaneous tunnel can reduce the incidence of postoperative intracranial infection.Bilateral ventricular drainage is more likely to have intracranial infection than unilateral extraventricular drainage.Urokinase perfusion,cerebrospinal fluid sampling,and prolonged catheterization increase the risk of intracranial infection.