布地奈德联合特布他林雾化吸入对儿童轻型支气管肺炎住院时间及呼出气一氧化氮的影响

Effects of budesonide combined with terbutaline atomization inhalation on hospitalization time and exhaled nitric oxide in children with mild bronchopneumonia

目的探讨布地奈德联合特布他林雾化吸入对儿童轻型支气管肺炎住院时间及呼出气一氧化氮(FeNO)的影响。方法选取2018年12月在潍坊市人民医院妇儿医院住院的支气管肺炎患儿40例,依照随机原则分为对照组和实验组,各20名。所有患儿常规抗生素控制感染,氨溴索化痰,实验组在此基础上加用布地奈德联合特布他林雾化吸入。比较两组治疗前后呼出气一氧化氮(FeNO)变化情况,并比较两组患儿症状改善时间与住院时间。结果治疗前,两组FeNO比较,差异无统计学意义。治疗后,两组FeNO均有下降,且实验组下降显著,差异有统计学意义(P<0.05)。实验组症状改善时间及住院时间均明显短于对照组,差异有统计学意义(P<0.05)。结论在冬季雾化吸入治疗儿童支气管肺炎,是一种行之有效的治疗方式。

Objective To study the effect of budesonide combined with terbutaline inhalation on the hospitalization time and the release of nitric oxide(FeNO)of the children with light bronchopneumonia.Methods Forty children with bronchopneumonia were randomly divided into control group(n=20)and experimental group(n=20)who were hospitalized in Women and Children's Hospital of Weifang People's Hospital in December 2018.The basic routine cure was for all the children patients in both control and experimental groups,including antibiotics to control infection and ammonia bromoxol to dissipate sputum.Additionally,the experimental children were treated with atomization inhalation of budesonide combined with terbutaline.The changes of exhaled nitric oxide(FeNO)were compared between the two groups before and after treatment,and the improvement time of symptoms and the length of hospitalization were in comparison between the two groups.Results Before treatment,there was no significant difference in FeNO between the two groups.After treatment,FeNO decreased in both groups,and significantly decreased in the experimental group(P<0.05).The improvement time of symptoms and the length of hospitalization in the experimental group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Atomization inhalation in winter is an effective treatment for bronchopneumonia in children.