直肠癌根治术后化疗病人希望与抑郁的相关性研究

Relationship between hope and depression among patients undergoing chemotherapy after radical resection of rectal neoplasms

目的调查直肠癌根治术后化疗病人希望的水平和抑郁情况,并探究两者之间的关系,为促进直肠癌根治术后化疗病人的心理健康提供依据。方法采用横断面调查法,选取2016年12月至2018年1月安徽省肿瘤医院(90例)和安徽医科大学第一附属医院(12例)两所医院直肠癌根治术后化疗的病人102例,使用Herth希望量表(HHI)和抑郁自评量表(SDS),分别测量病人的希望水平和抑郁情况。采用Pearson相关分析法分析希望与抑郁的相关性,采用多重线性回归分析法分析希望的影响因素。结果直肠癌病人希望得分为(34.62±4.19)分,抑郁得分为(47.73±8.92)分,抑郁的检出率为39.22%。相关分析表明直肠癌病人的希望水平与抑郁呈负相关(r=-0.475,P<0.05)。多重线性回归分析结果显示直肠癌根治术后化疗病人的化疗次数、病程、患病后工作状态、有无其他疾病、抑郁、肿瘤分期是希望的影响因素(P<0.05)。结论直肠癌根治术后化疗病人的希望处于中等水平,抑郁情况不容忽视。医务人员在医疗护理过程中应根据病人化疗次数、病程、患病后工作状态、有无其他疾病、肿瘤分期的特点制定适当的干预措施疏导病人的抑郁情绪,提高直肠癌病人的希望水平。

Objective To investigate the level of hope and depression in patients undergoing chemotherapy after radical resection of rectal neoplasms and to explore their relationship for promoting their mental health.Methods We adopted a cross?section survey,and a total of 102 patients undergoing chemotherapy after radical resection of rectal neoplasms from December 2016 to January 2018 were recruited,including 90 cases from Anhui Provincial Cancer Hospital and 12 cases from The First Affiliated Hospital of Anhui Medical University.The Herth Hope Index(HHI)and Depression self?rating scale(SDS)were used to measure the level of hope and depression of patients respectively.Pearson correlation analysis was used to analyze the correlation between hope and depression,and multiple linear regression analysis was used to analyze the influencing factors of hope.Results The hope score of patients with rec?tal neoplasms was(34.62±4.19)points,the depression score was(47.73±8.92)points,and the prevalence of depression was 39.22%.Correlation analysis showed that hope was negatively correlated with depression(r=-0.475,P<0.05).Multiple regression analysis showed that patients’times of chemotherapy,courses of diseases,working status after being ill,with or without other diseases,depres?sion,neoplasm staging were the influencing factors of hope(P<0.05).Conclusions Patients undergoing chemotherapy after radical resection of rectal neoplasms had moderate levels of hope and depression could not be ignored.Medical staff should take the charac?teristics,including times of chemotherapy,courses of diseases,working status after being ill,with or without other diseases,neoplasm staging of patients,into consideration and take appropriate intervention measures in the medical care process to decrease patients’depression and improve the level of hope for patients undergoing chemotherapy after radical resection of rectal neoplasms.