行小肠胶囊内镜检查CD患者胶囊滞留和未完成的相关因素分析

Analysis on Related Factors of Capsule Retention and Incomplete in Patients with CD by Small Intestine Capsule Endoscopy

目的:分析行小肠胶囊内镜检查克罗恩病(CD)患者临床特点及胶囊滞留和未完成的相关因素。方法:采用回顾性研究,收集本院106例行小肠胶囊内镜检查的CD患者的临床资料,记录患者临床特点,统计胶囊滞留和未完成的例数,采用多因素Logistic回归分析患者小肠胶囊内镜检查胶囊滞留和未完成的影响因素。结果:106例CD患者中,小肠胶囊内镜检查未完成13例,未完成率为12.26%。经多因素Logistic回归分析结果发现,性别、白蛋白、血红蛋白、腹泻是影响CD患者小肠胶囊内镜检查未完成的相关因素(P<0.05)。106例CD患者中,小肠胶囊内镜检查中胶囊滞留6例,滞留率为5.66%。6例胶囊滞留患者中,4例无任何临床症状(经药物治疗后自行排出胶囊),2例继发肠梗阻症状(经内镜取出胶囊),经对症治疗后顺利出院。结论:性别、白蛋白、血红蛋白及腹泻均是影响CD患者小肠胶囊内镜检查未完成的相关因素,临床中在胶囊内镜检查前应密切关注患者胃肠道动力和营养状况,排除肠道狭窄,尽可能降低检查未完成率,减少胶囊滞留的发生。

Objective:To analyze the clinical characteristics of patients with Crohn's disease(CD)who underwent small intestine capsule endoscopy and the related factors of capsule retention and incompleteness.Methods:A retrospective study was conducted to collect clinical data of 106 CD patients who underwent small intestinal capsule endoscopy in our hospital.The clinical characteristics of the patients were recorded.The number of cases of capsule retention and incompleteness was counted.Multivariate logistic regression was used to analyze the influencing factors of capsule retention and incompleteness in small intestine capsule endoscopy.Results:Among 106 CD patients,13 cases had not completed the small intestine capsule endoscopy,and the rate of incompleteness was 12.26%.Multivariate logistic regression analysis showed that gender,albumin,hemoglobin and diarrhea were related factors affecting the incompleteness of small intestinal capsule endoscopy in CD patients(P<0.05).Among 106 CD patients,6 cases were retained in small intestine capsule endoscopy,the retention rate was 5.66%.Of the 6 patients with capsule detention,4 had no clinical symptoms(capsules were discharged by themselves after drug treatment),2 had secondary intestinal obstruction(capsules were taken out by endoscopy).After symptomatic treatment,they were discharged smoothly.Conclusion:Gender,albumin,hemoglobin and diarrhea are all related factors affecting the incompleteness of small intestinal capsule endoscopy in CD patients.Before capsule endoscopy,we should pay close attention to the gastrointestinal motility and nutritional status of patients,exclude intestinal stricture,reduce the incomplete rate of examination as much as possible,and reduce the incidence of capsule retention.