界首市门诊和体检人群幽门螺杆菌感染状况调查

Study on Helicobacter pylori infection in health examination subjects and outpatients in Jieshou City,Anhui Province

目的调查界首地区门诊和体检人群幽门螺杆菌(H.pylori)感染流行病学特点,为现阶段H.pylori感染提供防治依据。方法收集2017年1月至2018年12月界首市人民医院门诊及体检中心到胃镜室以14 C-尿素呼气试验进行H.pylori感染检测人员的检测结果及一般情况进行回顾性分析。结果9 684例门诊和体检人群中,感染H.pylori 3032例(31.309%)。各年龄段H.pylori感染率差异有统计学意义(x^2=51.509,P<0.05),从18~39岁,随年龄增长,呈上升趋势,40岁以后,随年龄增长,呈下降趋势(x^2趋势=32.697,P<0.05)。不同居住状态H.pylori感染率差异有统计学意义(x^2=8.831,P<0.05),城镇高于农村。不同职业的H.pylori感染率差异有统计学意义(x^2=35.367,P<0.05),工人感染率最高,公务员感染率最低。各年度受检者H.pylori感染率差异无统计学意义(x^2=0.230,P>0.05)。结论界首地区门诊和体检人群H.pylori现症感染率低于全国水平,且感染分布与年龄、职业、居住环境相关。

Objective To investigate the epidemiological characteristics of Helicobacter pylori(H.pylori)infection in outpatients and patients of physical examination in Jieshou area,and to provide evidence for prevention and treatment of H.pylori infection at this stage.Methods The general conditions and results of 14 C-urea breath test in outpatient and physical examination center of Jieshou People’s Hospital from January 2017 to December 2018 were collected and analyzed retrospectively.Results Among 9,684 outpatient and physical examination population,3,032 cases(31.309%)were infected with H.pylori.There was significant difference in the infection rate of H.pylori among different age groups(x^2=51.509,P<0.05),the infection rate of H.pylori increased with age among the patients of 18 to 39 years old,while after 40 years old,the infection rate of H.pylori decreased with age(x^2 trend=32.697,P<0.05);There was significant difference in the infection rate of H.pylori among different living conditions(x^2=8.831,P<0.05),and the infection rate in urban areas was higher than that in rural areas;There was significant difference in the infection rate of H.pylori among different occupations(x^2=35.367,P<0.05),the infection rate of workers was the highest and that of civil servants was the lowest.There was no significant difference in the infection rate of H.pylori in each year(x^2=0.230,P>0.05).Conclusion The prevalence of H.pylori infection in outpatients and patients of physical examination in Jieshou District is lower than the average rate of the whole country,and the distribution of H.pylori infection is correlated with age,occupation and living environment.