摘要
基于在线富集-高效液相色谱-荧光法检测法,以C 18柱分别作为富集柱和分析柱,经优化荧光波长、色谱分离和富集条件,建立了同时快速检测塑料儿童水杯浸出液中9种双酚类物质的方法。方法学考察结果显示,所建方法符合含量测定要求。9种双酚类物质在各自范围内线性关系良好,相关系数(r^2)均大于0.998,检出限为0.13~66.7 ng/L。9种双酚类物质的回收率为90.7%~112.4%(RSD<11.3%,n=6)。结果显示,除双酚芴外,其他双酚类物质均有检出,浸出量随盛放时间增加而增大,高温多次浸泡后部分双酚类浸出量降低。该方法灵敏度高,操作简便,环境友好,可实现多种新型双酚类物质的同时快速检测。
A method was developed for the rapid determination of bisphenol A(BPA)and eight structural analogs in children’s plastic water bottles by online enrichment coupled with high performance liquid chromatography-fluorescence detection(HPLC-FLD).The correlation coefficients of the nine bisphenols were greater than 0.998.The limits of detection(LOQs)ranged from 0.13 ng/L to 66.7 ng/L.The recoveries ranged from 90.7%to 112.4%(RSD<11.3%,n=6).This method was applied to monitor nine bisphenols in children’s water bottles.The results showed that except 4,4′-(9 H-fluoren-9-ylidene)bisphenol(BPFL),all the remaining eight bisphenols were detected in different water bottles.The amounts of bisphenols leached increased with the increase of soaking time,and decreased after washing several times at 100℃.The proposed strategy is rapid,sensitive,reliable and eco-friendly,and is suitable for the simultaneous analysis of new bisphenols in water samples.
作者
韩疏影
宋易霖
康安
邓海山
朱栋
池玉梅
HAN Shuying;SONG Yilin;KANG An;DENG Haishan;ZHU Dong;CHI Yumei(College of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)
出处
《色谱》
CAS
CSCD
北大核心
2019年第11期1185-1192,共8页
Chinese Journal of Chromatography
基金
国家自然科学基金(81303311)
江苏省高校自然科学基金(17KJB360009)
江苏高校优势学科建设工程资助项目(PAPD)~~
关键词
高效液相色谱-荧光检测
在线富集
双酚类物质
塑料儿童水杯
high performance liquid chromatography-fluorescence detection(HPLC-FLD)
online enrichment
bisphenols
children’s plastic water bottles