磁共振波谱分析技术用于鉴别诊断乳腺良恶性病变的临床意义

Clinical Significance of Magnetic Resonance Spectroscopy in Differential Diagnosis of Benign and Malignant Breast Lesions

目的分析磁共振波谱分析技术(MRS)用于鉴别诊断乳腺良恶性病变的临床意义。方法选取2016年7月至2018年12月我院收治的乳腺病变患者87例,均接受MRS检查,以病理诊断结果为金标准,计算MRS诊断灵敏度、特异度、准确度。结果87例乳腺疾病患者中检出病灶91个,病灶大小1.0~6.2 cm,平均(2.74±0.61)cm。经病理结果证实恶性病灶、良性病灶分别为39个、52个;检出的91个病灶中,38个病灶在3.22~3.28 PPM时出现胆碱峰,53个未出现胆碱峰。以病理诊断结果为金标准,MRS诊断灵敏度、特异度、准确度分别为87.18%(34/39)、92.31%(48/52)、90.11%(82/91),MRS诊断乳腺良恶性病变与病理诊断结果一致性较高,Kappa值为0.797。结论MRS鉴别诊断乳腺良恶性病变的准确率高,利于提升疾病诊断效能,为疾病的临床诊治提供科学的影像学信息。

Objective To analyze the clinical significance of magnetic resonance spectroscopy(MRS)in differential diagnosis of benign and malignant breast lesions.Methods 87 cases of patients with breast lesions admitted to our hospital from July 2016 to December2018 were selected and examined by MRS.Taking the pathological diagnostic results as the gold standard,the diagnostic sensitivity,specificity and accuracy of MRS were calculated.Results 91 lesions were detected in 87 patients with breast diseases,the lesion size was 1.0 to 6.2 cm,and the average lesion size was(2.74±0.61)cm.39 malignant lesions and 52 benign lesions were confirmed by pathological results.38 of the 91 lesions were found to have choline peaks at 3.22 to 3.28 PPM,53 had no choline peaks.Taking the pathological diagnostic results as the gold standard,the diagnostic sensitivity,specificity and accuracy of MRS were 87.18%(34/39),92.31%(48/52)and90.11%(82/91)respectively.MRS had high consistency in diagnosis of breast benign and malignant lesions compared with pathological diagnosis results,with Kappa value of 0.797.Conclusions MRS has high accuracy in the differential diagnosis of benign and malignant breast lesions,which is conducive to improving the diagnostic efficiency of diseases and providing scientific imaging information for clinical diagnosis and treatment of diseases.