痰热清注射液联合阿奇霉素序贯治疗肺炎支原体肺炎患儿的疗效观察

Observation on Curative Effect of Tanreqing Injection Combined with Azithromycin Sequential Therapy in Children with Mycoplasma Pneumoniae Pneumonia

目的观察痰热清注射液联合阿奇霉素序贯治疗肺炎支原体肺炎患儿的临床效果。方法选取2016年9月至2018年12月我院收治的肺炎支原体肺炎患儿60例,根据治疗方式不同将其分为对照组和观察组各30例。对照组单独应用阿奇霉素治疗,观察组在对照组基础上采用痰热清注射液治疗,比较两组患儿治疗前后血清炎性因子水平、症状消退时间、住院时间及不良反应发生情况。结果治疗后,观察组的血清炎性因子水平均低于对照组(P<0.05)。观察组的症状消退时间及住院时间均短于对照组,且不良反应发生率低于对照组(P均<0.05)。结论痰热清注射液联合阿奇霉素序贯治疗在降低肺炎支原体肺炎患儿炎性反应、促进相关症状好转中均可发挥重要作用,且不良反应较少,值得临床推广应用。

Objective To observe the clinical effect of Tanreqing injection combined with azithromycin sequential therapy in children with mycoplasma pneumoniae pneumonia.Methods 60 children with mycoplasma pneumoniae pneumonia admitted to our hospital from September 2016 to December 2018 were selected and divided into control group and observation group according to the different treatment methods,with 30 cases in each group.The control group was only treated with azithromycin,and the observation group was treated with Tanreqing injection on the basis of the control group.The serum inflammatory factors before and after treatment,disappearance time of symptoms,hospitalization time and adverse reactions were compared between the two groups.Results After treatment,the levels of serum inflammatory factors in the observation group were lower than those in the control group(P<0.05).The disappearance time of symptoms and hospitalization time in the observation group were shorter than those in the control group,and the incidence of adverse reactions was lower than that in the control group(all P<0.05).Conclusions Tanreqing injection combined with azithromycin sequential therapy plays an important role in reducing inflammatory reaction of children with mycoplasma pneumoniae pneumonia,and promoting the improvement of related symptoms,with fewer adverse reactions,which is worthy of clinical promotion and application.