右美托咪定在ICU机械通气集束化治疗中的临床应用分析

Analysis on Clinical Application of Dexmedetomidine in ICU Mechanical Ventilation Clustering Therapy

目的分析右美托咪定应用于ICU机械通气集束化治疗中的临床效果。方法选取2017年12月至2018年12月于我院行ICU机械通气集束化治疗的68例患者,对照组(34例)采用咪达唑仑注射液进行镇静,研究组(34例)采用盐酸右美托咪定注射液进行镇静。比较两组患者的临床治疗指标及不良反应发生情况。结果治疗后,研究组的机械通气时间、ICU住院时间及拔管时间明显短于对照组(P<0.05)。研究组的不良反应发生率为5.88%,明显低于对照组的23.53%(P<0.05)。结论采用右美托咪定对ICU机械通气集束化治疗患者进行镇静,效果良好,且不良反应较少,有利于患者更快康复,值得临床推广应用。

Objective To analyze the clinical effect of dexmedetomidine in the application of ICU mechanical ventilation clustering therapy.Methods 68 patients with ICU mechanical ventilation clustering therapy in our hospital from December 2017 to December 2018 were selected.The control group(34 cases)was sedated with midazolam injection,and the study group(34 cases)was sedated with dexmedetomidine hydrochloride injection.The clinical treatment indicators and adverse reactions were compared between the two groups.Results After treatment,the mechanical ventilation time,ICU hospitalization time and extubation time of the study group were significantly shorter than those of the control group(P<0.05).The incidence of adverse reactions of the study group was 5.88%,significantly lower than23.53%of the control group(P<0.05).Conclusions Dexmedetomidine in the sedation of patients with ICU mechanical ventilation clustering therapy has good effect and fewer adverse reactions,which is conducive to faster recovery of patients,and is worthy of clinical promotion and application.