血液透析患者贫血与超敏CRP的相关性研究

Correlation Study Between Anemia and Hypersensitive C-reactive Protein in Hemodialysis Patients

目的探讨血液透析患者贫血与超敏CRP的相关性。方法选取2017年10月~12月我院行维持性血液透析患者86例,根据血透前超敏CRP水平分为正常组54例及增高组32例,比较两组血红蛋白水平,并分析其与超敏CRP相关关系。结果正常组血红蛋白为(122.22±22.32)g/L,高于增高组的(106.16±23.98)g/L,差异有统计学意义(P<0.05)。Pearson相关性结果显示,血红蛋白浓度和超敏CRP呈负相关(r=-0.358,P<0.05)。结论血液透析患者贫血与超敏CRP具有相关性,微炎症状态可能是导致血液透析患者血红蛋白水平较低的原因之一。

Objective To investigate the relationship between anemia and hypersensitive CRP in hemodialysis patients.Methods From October to December 2017,86 patients with maintenance hemodialysis were enrolled in our hospital.According to the level of hypersensitive CRP before hemodialysis,54 patients in the normal group and 32 patients in the elevated group were compared.The hemoglobin levels of the two groups were compared and analyzed.Hypersensitive CRP correlation.Results The hemoglobin of the normal group was(122.22±22.32)g/L,which was higher than that of the increased group(106.16±23.98)g/L,the difference was statistically significant(P<0.05).Pearson correlation results showed a negative correlation between hemoglobin concentration and hypersensitive CRP(r=-0.358,P<0.05).Conclusion Anemia in hemodialysis patients is associated with high-sensitivity CRP.Microinflammation may be one of the reasons for the lower hemoglobin levels in hemodialysis patients.