自体富血小板血浆联合关节镜下保留残端重建术治疗前交叉韧带损伤的临床研究

Clinical Study of PRP Combined with Arthroscopic ACL Reconstruction with Remnant Preservation in Treatment of Anterior Cruciate Ligament Injury

目的:探讨自体富血小板血浆(PRP)联合关节镜下保留残端前交叉韧带(ACL)重建术治疗前交叉韧带损伤对早期腱骨愈合的影响及安全性。方法:选取本院2014年5月至2017年9月收治的112例前交叉韧带损伤患者为研究对象,按照随机数表法将之分为对照组、观察组;对照组采用关节镜下保残重建术治疗,观察组采用PRP联合保残重建术治疗,对比两组患者治疗前后关节功能恢复水平,骨隧道恢复程度以及安全性等。结果:术前两组患者Lysholm以及KT-1000评分差异无统计学意义(P>0.05);术后两组患者Lysholm以及KT-1000评分随时间延长而升高,观察组患者在各时间点Lysholm以及KT-1000评分均明显高于对照组,差异有统计学意义(P<0.05)。观察组患者术后各时间点胫骨隧道恢复程度明显大于对照组,差异有统计学意义(P<0.05);观察组术后12个月IKDC优良率明显高于对照组,差异有统计学意义(P<0.05)。两组患者治疗及随访期并未出现相关并发症。结论:运用PRP联合关节镜下保留残端ACL重建术可更大程度促进患者腱骨的早期愈合,促进患者关节功能恢复,安全性高。

Objective:To investigate the effect of platelet-rich plasma(PRP)combined with arthroscopic anterior cruciate ligament(ACL)reconstruction with remnant preservation in treatment of Anterior cruciate ligament injury on early tendon-bone healing and safety.Methods:112 cases of knee ACL rupture treated in our hospital from May 2014 to September 2017 were selected and randomly divided into observation group and control group,with 25 cases in each group.The control group received the arthroscopic ACL reconstruction with remnant preservation,while the observation group received the PRP combined with arthroscopic ACL reconstruction with remnant preservation.Then the recovery of joint function and bone tunnel and safety were compared between the two groups.Results:Lysholm and KT-1000 scores had no difference between the two groups before operation(P>0.05),which were increased in both groups after operation,and were higher in the observation group than in the control group(P<0.05).The recovery degree of tibial tunnel in the observation group was significantly higher than that in the control group at each time point after operation(P<0.05);the excellent and good rate of IKDC in the observation group was significantly higher than that in the control group at the postoperative 12 months(P>0.05).There were no complications during the treatment and follow-up period in both groups.Conclusion:PRP combined with arthroscopic ACL reconstruction can promote early healing of tendons and bones in patients and improve the recovery of joint function with high safety.