中医体质与桥本氏甲状腺炎发病的相关性分析

Correlation Between TCM Constitution and the Onset of Hashimoto’s Thyroiditis

目的探讨中医体质与桥本氏甲状腺炎(HT)发病的相关性。方法确诊桥本氏甲状腺炎的门诊及住院患者共161例和健康对照组160例,采用调查表调查所有研究对象的中医体质类型和一般资料,HT患者抽取静脉血行甲功检查,对数据进行统计分析。结果平和体质HT患者FT3、FT4高于偏颇体质者,TSH、TPOAb和TGAb低于偏颇体质者(均P <0.05)。多因素分析结果显示HT的发生与性别、职业、吸烟、常食用海产品和体质类型存在相关性,女性、不稳定职业、吸烟、常食用海产品和偏颇体质发生HT风险高。结论 HT的发病与性别、职业、吸烟、常食用海产品和体质类型有关,体质因素在HT的发生发展中具有重要作用。

Objective To investigate the correlation between TCM constitution and the onset of hashimoto’s thyroiditis. Methods 161 outpatients and inpatients with Hashimoto’s thyroiditis and 160 healthy controls were enrolled. A questionnaire was used to investigate the TCM constitution types and general data of all subjects. HT patients underwent venous blood tests and statistical analysis was performed on the data. Results The FT3 and FT4 of HT patients with peaceful constitution were higher than those with biased constitution, and TSH, TPOAb and TGAb were lower than those with biased body(P < 0.01). Multivariate analysis showed that there was a correlation between the occurrence of HT and gender, occupation, smoking, eating seafood and physical types. Females, unstable occupations, smoking, eating seafood and biased physique had a high risk of HT. Conclusion The incidence of HT is related to gender, occupation, smoking, eating seafood and physical types. Physical factors play an important role in the occurrence and development of HT.