摘要
With the support by the National Natural Science foundation of China,the research team led by Prof.Chen Yue(陈悦)at the State Key Laboratory of Medicinal Chemical Biology,Nankai University,recently reported the first total synthesis,determination of the absolute configuration of the scaffold of ovatodiolide?Biological assays confirmed ovatodiolides can selectively ablate hepatic cancer stem cells(HCSCs).The research work was published in Angew Chem Int Ed(2019,131:10587-10590).
