促红细胞生成素联合左卡尼汀对血液透析肾性贫血患者的临床疗效

Clinical effect of erythropoietin combined with levocarnitine on hemodialysis patients with renal anemia

目的:分析促红细胞生成素(EPO)联合左卡尼汀对血液透析肾性贫血患者的临床疗效。方法:选取血液透析肾性贫血患者80例,根据不同治疗方案分为对照组和联合组各40例,对照组给予EPO治疗,联合组给予EPO联合左卡尼汀治疗。治疗3个月,比较两组患者的疗效。结果:联合组总有效率、血清相关指标改善情况均优于对照组;联合组平均EPO使用量、不良反应发生率均低于对照组(P<0.05)。结论:对血液透析肾性贫血患者应用EPO、左卡尼汀联合治疗,可以迅速增强血红蛋白浓度,提高血清铁蛋白水平,改善患者贫血症状,减少了EPO的使用量,且不良反应发生率低。

Objective:To analyze the clinical effect of erythropoietin(EPO)combined with levocarnitine in the treatment of the hemodialysis patients with renal anemia.Methods:Eighty cases of hemodialysis patients with renal anemia were selected and divided into a control group and a combined group with 40 cases each according to different treatment options.The control group was treated with EPO while the combined group was treated with EPO and levocarnitine after hemodialysis.The treatment was lasted for 3 months and the effects were compared between the two groups.Results:The total effective rate and the improvement of serum related indexes were better and the average EPO usage and the incidence of adverse reactions were lower in the combined group than the control group(P<0.05).Conclusion:EPO combined with levocarnitine can rapidly increase the hemoglobin concentration,raise the level of serum ferritin,improve the anemia symptoms and reduce EPO usage with lower incidence of adverse reactions.