对比剂（CuSO4溶液）浓度对磁共振成像弛豫时间的影响研究

Study for Effect of Contrast Agent（CuSO4 Solution）Concentration on Relaxation Time of Magnetic Resonance Imaging

目的:利用原子核自身的磁性及其与外加磁场的作用(NMR),来探究硫酸铜(CuSO 4)溶液中氢原子核的磁共振弛豫时间T(纵向弛豫时间T 1,横向弛豫时间T 2)随CuSO 4溶液浓度变化所呈现的关系.方法:实验中用不同浓度的CuSO 4稀溶液代替对比剂来调节氢核的弛豫时间,用FD-PNMR-C型脉冲核磁共振实验仪测定CuSO 4溶液的弛豫时间T 1及T 2,研究不同浓度的CuSO 4作为杂质对水分子中氢核弛豫时间的影响规律,并画出各弛豫时间与CuSO 4溶液浓度变化的关系图.结果:弛豫时间常数T随CuSO 4溶液浓度的增大而减小.结论:弛豫时间常数的大小受溶液浓度影响,在误差允许的范围内对实验结果进行分析,得出了弛豫时间常数与溶液浓度成反比的规律.

Objective:To make use of the magnetic properties of the nucleus itself and its interaction with the external magnetic field(NMR).To explore the relationship between the magnetic resonance relaxation time T(longitudinal relaxation time T 1,transverse relaxation time T 2)of hydrogen nuclei in copper sulfate(CuSO 4)solution and the change in the concentration of CuSO 4 solution.Methods:The relaxation time of hydrogen nuclei was adjusted by using different concentration of CuSO 4 dilute solution instead of contrast agent.The relaxation time of CuSO 4 solution was determined by FD-PNMR-C pulsed nuclear magnetic resonance tester.The effects of different concentrations of CuSO 4 as an impurity on the relaxation time of hydrogen nuclei in water molecules were studied,and the relationship between the relaxation time and the concentration of CuSO 4 solution was drawn.Results:The relaxation time constant T decreased with the increase of the concentration of CuSO 4 solution.Conclusion:The size of relaxation time constant is affected by the concentration of solution,and the experimental results are analyzed within the range of error,and the rule that the relaxation time constant is inversely proportional to the concentration of solution is obtained.