上肢PICC置管化疗在伴隐匿上腔静脉综合征胸腔肿瘤患者中的应用效果

Effect of upper limb PICC catheter chemotherapy in patients with thoracic tumors with occult superior vena cava syndrome

目的探讨胸腔肿瘤伴隐匿上腔静脉综合征(SVCS)患者行上肢PICC置管化疗的安全性。方法选取2017年1月~2019年1月我院收治的60例SVCS患者,根据血管通路建立方式分成观察组和对照组,每组各30例。观察组行上肢PICC置管,对照组行下肢PICC置管,对比两组症状改善程度、相关并发症发生情况与生活质量评分。结果治疗后,两组的病情改善情况比较,差异无统计学意义(P>0.05);观察组导管相关并发症发生率低于对照组,差异有统计学意义(P<0.05);观察组生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论胸腔肿瘤伴SVCS者,通过上肢PICC置管实行化疗具有一定可行性与安全性,加上实施有效的安全管理,不仅导管并发症发生率不会增加,患者生活质量还可显著提高。

Objective To explore the safety of upper limb PICC catheter chemotherapy in patients with thoracic tumors with occult superior vena cava syndrome(SVCS).Methods From January 2017 to January 2019,60 patients with superior vena cava admitted to our hospital from January 2017 to January 2019 were selected,according to the vascular access mode was divided into observation group and control group,30 cases in each group.The observation group was upper limbs routine PICC catheter,the control group was routine lower limb PICC catheter,Improvement of symptoms,related complications and improve quality of life scores were compared between two groups.Results After treatment,there was no significant difference between the two groups in the improvement of superior vena cava syndrome(P>0.05).The incidence of catheter-related complications in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The quality of life score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with thoracic tumors accompanied by occult SVCS,chemotherapy through upper limb PICC catheterization is feasible and safe to some extent.In addition,effective safety management can be carried out to prevent the incidence of catheter complications and significantly improve the quality of life of patients.