卡贝缩宫素在剖宫产术中的应用效果

Application effect of Carbetocin in cesarean section

目的探讨卡贝缩宫素在剖宫产术中的应用效果。方法选取2018年1~12月我院收治的100例行剖宫产的产妇作为研究对象,根据随机数字表法分为研究组(50例)与对照组(50例)。对照组产妇应用缩宫素,研究组产妇应用卡贝缩宫素。比较分析两组产妇的出血量情况、间接出血指标以及药物不良反应发生情况。结果研究组产妇的术中出血量、术后2、24 h出血量均低于对照组,差异有统计学意义(P<0.05);研究组产妇的血红蛋白、红细胞比容、收缩压、舒张压水平均高于对照组,差异有统计学意义(P<0.05);研究组产妇的心率低于对照组,差异有统计学意义(P<0.05);研究组的不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论在剖宫产术中,给予产妇卡贝缩宫素预防产后出血的效果确切,安全性高,值得推广。

Objective To investigate the effect of Carbetocin in cesarean section.Methods A total of 100 women undergoing cesarean section from January to December 2018 were selected as the subjects.They were divided into study group(50 cases)and control group(50 cases)according to the random number table method.The control group was treated with Oxytocin,and the study group was treated with Carbetocin.The blood loss,indirect bleeding,and adverse drug reactions were compared.Results The intraoperative bleeding volume,2 h postoperatively bleeding volume,24 h postoperatively bleeding volume in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).The hemoglobin,hematocrit,systolic blood pressure,diastolic blood pressure in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The heart rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).The total incidence rate of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion In cesarean section,the application of Carbetocin in the treatment of postpartum hemorrhage is effective and safe,which is worth popularizing.