口腔种植修复对牙列缺失患者局部炎症反应及牙功能的影响

Effect of oral implant restoration on local inflammatory reaction and dental function in patients with dentition loss

目的探讨口腔种植修复对牙列缺失患者局部炎症反应及牙功能的影响。方法选取2016年1月~2018年1月我院收治的30例牙列缺失患者作为研究对象,按照随机数字表法将其分为观察组(15例)和对照组(15例)。观察组患者采用口腔种植修复,对照组患者采用常规修复。比较两组患者的临床疗效、治疗前后牙功能、牙龈状态评分、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、白介素-8(IL-8)水平及并发症发生情况。结果观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05)。两组患者治疗前的牙功能、牙龈状态评分比较,差异无统计学意义(P>0.05);两组患者治疗后的牙功能评分均高于治疗前,牙龈状态评分均低于治疗前,差异有统计学意义(P<0.05);观察组患者治疗后的牙功能评分高于对照组,牙龈状态评分低于对照组,差异有统计学意义(P<0.05)。两组患者治疗前的TNF-α、IL-6、IL-8水平比较,差异无统计学意义(P>0.05);两组患者治疗后的TNF-α、IL-6、IL-8水平均高于治疗前,差异有统计学意义(P<0.05);观察组患者治疗后的TNF-α、IL-6、IL-8水平均低于对照组,差异有统计学意义(P<0.05)。观察组患者的并发症总发生率为13.33%,明显低于对照组的40.00%,差异有统计学意义(P<0.05)。结论口腔种植修复在牙列缺失患者中的应用效果肯定,能够减轻局部炎症反应,改善牙功能。

Objective To investigate the effect of oral implant restoration on local inflammatory reaction and dental function in patients with dentition loss.Methods Thirty patients with dentition loss from January 2016 to January 2018 in our hospital were enrolled in the study.They were divided into observation group(15 cases)and control group(15 cases)according to the random number table method.Patients in the observation group received oral implant restoration,and patients in the control group received routine repair.The clinical efficacy,dental function,gingival state scores,tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),interleukin-8(IL-8)levels before and after treatment and incidence of complications were compared between the two groups.Results The total effective rate of the treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in the scores of dental function and gingival state between the two groups before treatment(P>0.05).The dental function scores of the two groups after treatment were higher than those before treatment,the gingival state scores were lower than before treatment,and the differences were statistically significant(P<0.05).The dental function scores in the observation group after treatment were higher than those in the control group,the gingival state scores were lower than in the control group,and the differences were statistically significant(P<0.05).There were no significant differences in the levels of TNF-α,IL-6 and IL-8 between the two groups before treatment(P>0.05).The levels of TNF-α,IL-6 and IL-8 in the two groups after treatment were higher than those before treatment,and the differences were statistically significant(P<0.05).The levels of TNF-α,IL-6 and IL-8 in the observation group after treatment were lower than those in the control group,and the differences were statistically significant(P<0.05).The total incidence rate of complications in the observation group was 13.33%,which was significantly lower than that in the control group(40.00%),and the difference was statistically significant(P<0.05).Conclusion The application effect of oral implant restoration in patients with dentition loss is positive,which can alleviate local inflammatory reaction and improve dental function.