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X线引导硬膜外腔神经根松解联合注射药物治疗腰椎间盘突出症疗效观察 被引量:9

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摘要 腰椎间盘突出症(lumbar disc herniation,LDH)是一种因椎间盘退变和损伤造成纤维环破裂、髓核突出,压迫或刺激相应节段神经根或马尾神经所表现出的一种临床综合症常见症状为腰腿疼痛,发病率约为20%~30%[1]。目前认为其发病机制主要有机械压迫学说、化学性神经根炎学说和自身免疫学说,其中炎症反应是LDH引起腰腿痛最重要的发病机制,炎症因子的含量与腰椎间盘退变、突出和坐骨神经痛的发生均有密切关系[2]。约80%~90%的LDH病人经保守治疗后可缓解临床症状或临床治愈,LDH经保守治疗超过3个月无效时可考虑开放手术[3]。
作者 张在青 陈波
出处 《中国疼痛医学杂志》 CAS CSCD 北大核心 2019年第9期715-717,共3页 Chinese Journal of Pain Medicine
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