两种不同形态MnO2降解卡马西平的效果及途径对比

Studies on degradation of carbamazepine by two different forms of MnO2

研究了两种不同形态MnO2(δ-MnO2和胶体MnO2)对难降解有机药物卡马西平(carbamazepine,CBZ)的去除效果,并通过液相色谱质谱联用技术(LC/MS)分析了不同pH值条件下δ-MnO2和胶体MnO2氧化转化CBZ的产物,探究其氧化转化途径.结果表明,δ-MnO2和胶体MnO2能通过化学氧化作用在2h内去除约1mg/L CBZ,相比之下,胶体MnO2受pH影响较小且单位质量Mn对CBZ具有更好的去除效果.δ-MnO2和胶体MnO2与CBZ反应过程中各检出7种和4种产物.胶体MnO2具有更强的氧化能力,越过了多种中间产物的产生步骤,使CBZ的降解途径更加简明.

Degradation of carbamazepine(CBZ)by two different forms of MnO2(δ-MnO2 and colloidal MnO2)was studied and compared.The intermediate products in CBZ oxidation at different pH byδ-MnO2 or colloidal MnO2 were analysed via LC/MS.Results demonstrated that 1mg/L of CBZ could be completely removed by bothδ-MnO2 and colloidal MnO2 within 2 hours.Comparing toδ-MnO2,colloidal MnO2 was less affected by pH and had better removal of CBZ per unit mass Mn.In total,7 and 4 kinds of intermediate products were detected in the process of CBZ oxidation byδ-MnO2 and colloidal MnO2,respectively.That was because colloidal MnO2 had stronger oxidizing power,and could omit several oxidation steps producing various intermediates.As a result,CBZ oxidation by colloidal MnO2 was via a more concise pathway.