某精神专科医院药学干预对二类精神药品使用的影响

Effects of Clinical Pharmacists Intervention on the Use of Psychotropic Drugs of Category Ⅱ in a Psychiatric Hospital

目的探讨在药学合理干预下,某精神专科医院住院患者二类精神药品不合理用药发生率的改善情况,为进一步加强二类精神药品管理提供参考。方法利用合理用药监测系统(prescription automatic screening system,PASS)和HIS系统(hospital information system,HIS)对某精神专科医院药学干预前一年2016年8月至2017年7月住院患者的447 694条二类精神药品医嘱、药学干预后一年2017年8月至2018年7月447 853条二类精神药品医嘱进行分析。结果药学合理干预后,二类精神药品问题医嘱由干预前的2 023条降至1 363条;问题医嘱重复出现的次数由干预前的1 003条降至711条;潜在不良反应、剂量不合理、药物相互作用、重复用药相关的问题医嘱明显降低(P<0.01)。结论通过药学合理干预,某精神专科医院二类精神药品的不合理使用发生率整体降低。

Objective To explore the effects of pharmacists intervention on the incidence of irrational use of psychotropic drugs of categoryⅡfor hospitalized patients in a psychiatric hospital,so as to provide reference for further strengthening the management of categoryⅡpsychotropic drugs.Methods Prescription automatic screening system(PASS)and HIS system were used to analyze the 447 694 orders of psychotropic drugs of categoryⅡfrom August 2016 to July 2017 before pharmacists intervention and 447 853 orders after intervention from August 2017 to July 2018 in a psychiatric hospital.Results After intervention by clinical pharmacists,the number of prescribing errors of psychotropic drugs of categoryⅡwas decreased from 2 023 to 1 363,and the duplicated errors decreased from 1 003 to 711.Moreover,prescribing errors include potential adverse drug reaction,incorrect dosage,drug interaction and duplicate prescription were significantly decreased(P<0.01).Conclusion The incidence of irrational use of psychotropic drugs of categoryⅡin a psychiatric hospital was reduced under the intervention by clinical pharmacists.