围绝经期女性接受太极拳运动后骨密度的变化

Effects of Tai Chi Chuan on the changes of bone mineral density of perimenopausal women

背景:当前练习太极拳对围绝经期综合征和骨密度有何影响鲜有文献报道。目的:探讨定期的太极拳锻炼对围绝经期女性症状、血浆多巴胺、血浆β-内啡肽和骨密度的影响。方法:该研究方案的实施符合西南科技大学对研究的相关伦理要求,受试者对试验过程完全知情同意。选取74名年龄分布在45-55岁的围绝经期女性,采用数字随机方式分为太极组(n=36)和对照组(n=38),太极组进行为期48周(3次/周,60 min/次)的太极拳锻炼;对照组除保持既往生活习惯外不再进行其他方式的锻炼。测试两组受试者48周前后Kupperman量表的评分,多巴胺和β-内啡肽浓度、腰椎和优势侧股骨近端骨密度。结果与结论:①48周后太极组潮热出汗、感觉异常、失眠、焦躁、眩晕、抑郁、疲乏、肌肉关节痛和Kupperman总分极显著减小(P<0.01)且极显著小于对照组(P<0.01),多巴胺和β-内啡肽浓度极显著增加(P<0.01),腰椎L2-4、股骨颈、大转子和Ward’s三角骨密度无显著变化(P>0.05);②多巴胺浓度与失眠、抑郁和Kupperman总分呈显著负相关(P<0.05),β-内啡肽浓度与失眠、焦躁和Kupperman总分呈显著负相关(P<0.05);③结果说明,48周太极拳锻炼显著改善了围绝经期女性症状,提示血浆多巴胺和β-内啡肽浓度变化是减轻围绝经症状的因素之一,但对腰椎和股骨近端骨密度无显著影响。

BACKGROUND:There are few reports about the effects of Tai Chi Chuan on perimenopausal syndrome and bone mineral density.OBJECTIVE:To investigate the effects of regular Tai Chi Chuan exercise on symptoms,plasma dopamine,plasma beta-endorphin and bone mineral density in perimenopausal women.METHODS:The study was in accordance with the ethical requirements of Southwest University of Science and Technology,and all participants signed the informed consents.Totally 74 perimenopausal women aged 45-55 years were randomly divided into two groups:Tai Chi group(n=36)and control group(n=38).Taichi group took Tai Chi Chuan for 48 weeks(thrice a week,60 minutes/times).The control group went on previous habits only.The scores of Kupperman scale,dopamine,beta-endorphin,and bone mineral density of lumbar spine and proximal femur were measured before and after 48 weeks.RESULTS AND CONCLUSION:(1)After 48 weeks,the total scores of hot flashes,sweating,dysesthesia,insomnia,restlessness,vertigo,depression,fatigue,muscular and articular pain and Kupperman scale cores in the Tai Chi group were decreased significantly(P<0.01),and were significantly lower than those in the control group(P<0.01).The concentrations of dopamine and beta-endorphin were increased significantly(P<0.01).There were no significant changes in bone mineral density of L2-4,femoral neck,trochanter and Ward’s triangle(P>0.05).(2)Dopamine concentration was negatively correlated with insomnia,depression and Kupperman total score(P<0.05),while beta-endorphin concentration was negatively correlated with insomnia,anxiety and Kupperman total score(P<0.05).(3)In summary,48-week Tai Chi Chuan exercise can significantly improve the symptoms of perimenopausal women,suggesting that the changes of plasma dopamine and beta-endorphin levels are one of the factors to alleviate the symptoms of perimenopause.However,there is no significant effect on bone mineral density of lumbar spine and proximal femur.