摘要
副猪嗜血杆菌(HPS)能够引起猪的脑膜炎、多发性浆膜炎、关节炎、急性肺炎和急性败血症为主要特征的猪革拉泽氏病。脂多糖(LPS)是革兰阴性菌外膜的主要成分,在致病机制中起着重要作用。论文对HPS的LPS结构、基因特征和致病机制进行综述,旨在为探索HPS LPS的相关毒力基因及对HPS LPS致病机制研究提供参考。
Haemophilus parasuis(HPS)can cause Gl ser s disease,which is characterized by fibrinous polyserositis,arthritis,meningitis,acute pneumoniae and acute septicaemia.Lipopolysaccharide(LPS)is the major constituent of the outer membranes of Gram-negative bacteria and has a great influence on pathogenesis.In this article,the structure,gene feature and pathogenesis of HPS LPS were discussed,which is helpful to explore the virulence associated gene and the pathogenesis of HPS LPS.
作者
曾泽
张华琦
桂干北
綦世金
刘杉杉
张斌
ZENG Ze;ZHANG Hua-qi;GUI Gan-bei;QI Shi-jin;LIU Shan-shan;ZHANG Bin(Tongren Vocational Technical College,Tongren,Guizhou,554300,China;College of Life Science and Technology,Southwest Minzu University,Chendu,Sichuan,610041,China;Collaborative Innovation Center of Guizhou Province Livestock and Poultry Healthy Breeding,Tongren,Guizhou,554300,China;Engineering Research Center of Safe and Efficient Application of Guizhou Province Feed Forage,Tongren,Guizhou,554300,China)
出处
《动物医学进展》
北大核心
2019年第10期84-89,共6页
Progress In Veterinary Medicine
基金
贵州省科技计划项目(黔科合基础[2019]1314号)
铜仁市科技计划项目(铜市科研[2018]34号)
贵州省星火计划项目(黔科合成转字[2015]5326-1号)
关键词
副猪嗜血杆菌
脂多糖
基因特征
致病机制
Haemophilus parasuis
lipopolysaccharide
gene feature
pathogenesis
