血清维生素A维生素E水平与孕妇子痫前期的关系分析

Correlation between serum vitamin A and E levels and preeclampsia in pregnant women

目的研究血清维生素A和维生素E与孕妇子痫前期的关系。方法选取我院妊娠期子痫前期患者156例(包括66例轻度子痫前期患者为A组,90例重度子痫前期患者为B组),健康孕产妇80名,分别检测3组患者血清维生素A、E含量,比较其与子痫前期相关性。结果重度子痫前期组孕妇血清维生素A含量低于轻度子痫前期组和对照组;维生素E含量低于轻度子痫前期组和对照组。Spearman相关分析提示子痫前期孕妇血清中维生素A、E含量异常与子痫前期存在直接相关关系。结论妊娠期维生素A、E与子痫前期的发生具有重要相关性,应加强对孕期维生素A、E水平监测,及时预防。

Objective To investigate the correlation between serum vitamin A and E levels and preeclampsia in pregnant women.Methods Included in this study were a total of 156 pregnant women with preeclampsia in our hospital(including 66 with mild preeclampsia as group A and 90 with severe preeclampsia as group B),and 80 normal pregnant women.Serum vitamin A and E levels were measured in the three groups,and their correlation with preeclampsia was compared.Results The severe preeclampsia group showed lower serum vitamin A level and lower vitamin E level than those in the mild preeclampsia group and control group.Spearman correlation analysis indicated that abnormal serum vitamin A and E levels were directly related to preeclampsia in the groups A and B.Conclusions Vitamin A and E levels in pregnancy are closely related to the occurrence of preeclampsia.Therefore,it is important to enhance the monitoring of vitamin A and E levels in pregnancy from a perspective of timely prevention againstpreeclampsia.