超声造影及介入在周围型肺部病变诊断中的应用价值分析

Diagnostic value of contrast-enhanced ultrasonography and interventional therapy in peripheral pulmonary lesions

目的探讨对周围型肺部病变患者选择超声造影以及介入方法完成病灶诊断后获得的临床价值。方法选择本院2017年11月至2019年01月收治的68例周围型肺部病变患者作为实验对象;选择常规超声方法对患者完成病灶诊断后,再选择超声造影方法对病灶展开进一步检查,并且通过超声引导,针对患者不同造影增强区域展开经皮肺穿刺活检操作,对结果展开分析。结果临床对病灶完成超声造影后,由相对专业或经验丰富的老师通过对造影结果进行分析,合理完成对应分型操作,其中28例患者属于Ⅰ型均匀增强型;36例属于Ⅱ型不均匀增强型;4例属于Ⅲ型环状增强型;通过对开始增强时间进行观察,合理完成对应分型操作,12例患者属于Ⅰ型7~9 s;48例属于Ⅱ型10~15 s;8例属于Ⅲ型>15 s;通过超声引导,针对周围型肺部病变实施穿刺活检后发现,52例患者获得恶性结果,其中包括8例鳞癌疾病患者,28例腺癌疾病患者;此外包括2例淋巴瘤患者,10例小细胞神经内分泌癌患者以及4例间皮瘤患者;16例患者获得良性结果,其中包括2例炎性假瘤患者,4例炎症患者以及2例萎缩肺组织患者。结论周围型肺部病变患者进行了超声造影以及介入诊断,效果确切,针对造影后表现出的高增强区域合理展开超声引导下穿刺活检,可以将穿刺阳性率显著提升,从而对于周围型肺部病变患者进行有效治疗以及康复状态的提升,提供一定的临床价值。

Objective To explore the clinical value of contrast-enhanced ultrasound(CEUS)and interventional therapy in the diagnosis of peripheral pulmonary lesions.Methods 68 patients with peripheral pulmonary disease admitted to our hospital from November 2017 to January 2019 were selected as experimental subjects.After the conventional ultrasound method was selected for the diagnosis of the lesions,the contrastenhanced ultrasound method was selected for further examination of the lesions.In addition,percutaneous lung biopsy was conducted for different contrast-enhanced areas of the patients under the guidance of ultrasound,and the results were analyzed.Results The clinical lesions,after completion of ultrasonic imaging by the relative professional and experienced staff,through analysis of imaging results,should be completed with reasonable type of operation,there were 28 cases of type Ⅰ homogeneous enhancement,36 cases of type Ⅱ uneven enhancement,4 cases of type Ⅲ annular enhancement.Through the observation on the time to arrival,should be completed with reasonable type of operation,there were 12 cases of typeⅠ7-9 s,48 cases of type Ⅱ 10-15 s,8 cases of type Ⅲ>15 s.Ultrasound guided biopsy for peripheral lung lesions revealed 52 patients with malignant results,including 8 patients with squamous cell carcinoma,28 patients with adenocarcinoma,2 patients with lymphoma,10 patients with small cell neuroendocrine carcinoma,and 4 patients with mesothelioma.Benign results were obtained in 16 patients,including 2 patients with inflammatory pseudotumor,4 patients with inflammation,and 2 patients with atrophic lung tissue.Conclusions For patients with peripheral lung lesions,ultrasonic imaging and interventional diagnostic effect is exact;for high enhancement region showed by ultrasonography,reasonable ultrasound guided biopsy can significantly increase positive puncture rate,which provides certain clinical value for effective treatment and the improvement of rehabilitation state for patients with peripheral lung lesions.