摘要
根据荧光探针设计原理和香豆素及喹啉类化合物的特性,以7-二乙基氨基香豆素-3-醛和4-(4-甲基喹啉-1-烯-1-基)丁烷-1-磺酸盐为原料,设计合成了一种新型香豆素-喹啉类荧光探针XDS-1,用红外光谱和核磁共振表征了XDS-1的结构,用紫外-可见吸收光谱、荧光光谱测试了其光谱特性。结果表明合成的XDS-1紫外-可见吸收光谱波长长,荧光发射波长长,Stokes位移大。
According to the design principle of fluorescent probe and the characteristics of coumarin and quinoline compound,a novel coumarin-quinoline fluorescent probe(XDS-1)was synthesized by using 7-diethylaminocoumarin-3-aldehyde and 4-(4-methylquinolin-1-en-1-yl)butane-1-sulfonate as raw materials.The structure of XDS-1 was characterized by Fourier infrared spectroscopy and nuclear magnetic resonance.The spectral properties of XDS-1 was tested by UV-vis spectrum and Fluorescence spectroscopy.The results showed that the synthesized XDS-1 has a long ultraviolet-visible absorption wavelength,a long fluorescence emission wavelength,and a large Stokes shift.
作者
林大勇
付江堂
周婷婷
祝晶晶
谷迎春
任雪玲
Lin Dayong;Fu Jiangtang;Zhou Tingting;Zhu Jingjing;Gu Yingchun;Ren Xueling(Anda Duosen New Material Technology Co.,Ltd.,Anda 151400,China;Qiqihar Longzhu Dope Co.,Ltd.,Qiqihar 151400,China;Tianjin Engineering Technology Center of Chemical Wastewater Source Reduction and Recycling,School of Science,Tianjin Chengjian University,Tianjin 300384,China;Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases,School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China)
出处
《山东化工》
CAS
2019年第19期1-2,6,共3页
Shandong Chemical Industry
基金
国家自然科学基金项目(21502137)
河南省肿瘤重大疾病靶向治疗和诊断重点实验室开放课题资助项目(NMZL2018101)
关键词
香豆素-喹啉
荧光探针
光谱特性
coumarin-quinoline
fluorescent probe
spectral properties
