空腹血糖、糖化血红蛋白检测在初发2型糖尿病患者诊断及疗效评价中的临床价值分析

Exploration on the clinical value of detecting fasting blood glucose and glycosylated hemoglobin in the diagnosis and evaluation of curative effects of patients with new-onset of type 2 diabetes mellitus

目的探讨空腹血糖(FBG)、糖化血红蛋白(HbAlC)检测在初发2型糖尿病患者诊断及疗效评价中的临床价值。方法将2016年1月~2017年12月在我院接受治疗的30例初发2型糖尿病患者作为观察组,并将同期在我院健康体检的30名正常者作为对照组,对两组FBG、HbAlC指标予以检测,并对观察组患者接受治疗3、6个月FBG、HbAlC指标予以检测,探究其疗效评估价值。结果观察组患者FBG、HbAlC、2h PG指标显著高于对照组,血清C肽指标较对照组低,差异有统计学意义(P<0.05);观察组患者接受治疗后3、6个月FBG、HbAlC指标均显著低于治疗前,差异有统计学意义(P<0.05)。结论空腹血糖、糖化血红蛋白检测能够用于初发2型糖尿病诊断,对其治疗效果予以评估,具有较高临床价值。

Objective To explore the clinical value of detecting fasting blood glucose(FBG)and glycosylated hemoglobin(HbAlC)in the diagnosis and evaluation of curative effects of patients with new-onset of type 2 diabetes mellitus.Methods 30 patients with new-onset of type 2 diabetes mellitus who were treated in our hospital from January 2016 to December 2017 were selected as the observation group.30 people who underwent physical health examinations in our hospital during the same period were selected as the control group.FBG and HbAlC of the two groups were detected.And FBG and HbAlC of patients in the observation group were detected after 3 months and 6 months of treatment.The values of evaluation of curative effects were explored.Results The FBG,HbAlC and 2h PG of the observation group were significantly higher than those of the control group,the serum C peptide index was lower than that of the control group(P<0.05),and the differences were statistically significant.FBG and HbAlC of patients in the observation group after 3 months and 6 months of treatment were significantly lower than those before the treatment(P<0.05),and the differences were statistically significant.Conclusion Fasting blood glucose and glycosylated hemoglobin detection can be used in the diagnosis of new-onset of type 2 diabetes mellitus and evaluation of curative effects of it,which has higher clinical values.