机械取栓治疗急性大面积脑梗死的疗效

The curative effect of mechanical thrombectomy in treatment of acute massive cerebral infarction

目的探讨对急性脑梗死患者应用机械取栓治疗的效果。方法选取2017年7月~2018年7月收治的96例急性脑梗死患者,将其按照随机数字表法分组,依次采用机械取栓治疗和动静脉联合溶栓治疗,每组48例患者,依次设定为观察组和对照组。结果观察组的治疗总有效率(97.92%)较对照组(81.26%)高(χ2=28.196,P<0.05)。观察组治疗后不同时间段的各项指标(NIHSS评分、Barthel Index指数)均优于对照组(P<0.05)。此外,血管再通率方面,观察组和对照组分别为97.92%、83.33%(P<0.05)。24h颅内出血率:观察组和对照组分别为2.08%、14.58%(P<0.05)。随访3个月内急性脑梗死的病死率,对照组和观察组分别为10.42%、2.08%(P<0.05)。结论与其他治疗方案相比,对于大血管梗塞引起的大面积脑梗死,机械取栓治疗急性脑梗死取得了更显著的效果,此方案既能有效改善患者血管再通率,又能提升治疗总有效率,远近期疗效均比较好,故方案推广意义显著。

Objective To explore the curative effect of mechanical thrombectomy in treatment of patients with acute cerebral infarction by the experiment.Methods 96 patients with acute cerebral infarction who were admitted and treated in our hospital from July 2017 to July 2018 were selected.According to the random number table,they were divided into the observation group and the control group,with 48 cases in each group.They were respectively treated with mechanical thrombectomy and combined intravenous and intra-arterial thrombolysis.Results The total effective rate(97.92%)in the observation group cases were higher than 81.26%in the control group(χ2=28.196,P<0.05).All indexes(NIHSS and Barthel Index)in the observation group were better than those in the control group at different time periods after treatment(P<0.05).In addition,the vascular recanalization rates of the observation group and the control group were 97.92%and 83.33%,respectively(P<0.05).Intracranial hemorrhage rates within 24 hours of the observation group and the control group were respectively 2.08%and 14.58%(P<0.05).The mortality rates of acute cerebral infarction in three-month follow-up in the control group and the observation group were respectively 10.42%and 2.08%(P<0.05).Conclusion Compared with other treatments,mechanical thrombectomy in treatment of massive cerebral infarction caused by great vessel infarctionachieves more significant curative effects.It can not only effectively improve the vascularrecanalization rate,but also improve the total effective rate of treatment.Both shortterm and long-term curative effects are relatively good,so it has great significance in promoting the treatment scheme.