凉血通瘀方治疗瘀热型急性脑梗死

Treatment of Stasis-type Acute Cerebral Infarction with Liangxue Tongyu Decoction

目的:观察凉血通瘀方治疗急性脑梗死的临床疗效。方法:98例瘀热型急性脑梗死患者随机分为对照组和观察组各49例。对照组给予常规治疗,观察组在对照组治疗基础上口服或鼻饲凉血通瘀方。2周后比较两组患者血脂、D-二聚体、梗死灶面积、NIHSS评分及中医证候疗效。结果:治疗后,与治疗前比较,两组患者D-二聚体水平均显著下降(P<0.01),且观察组治疗后D-二聚体水平低于对照组治疗后(P<0.01)。治疗后,两组梗死灶面积小于治疗前,观察组梗死面积缩小率优于对照组(P<0.01)。治疗后,两组NIHSS评分及中医证候积分均低于治疗前(P<0.01),且观察组低于对照组(P<0.01)。对照组有效率为73.47%,观察组有效率为95.92%,观察组有效率高于对照组(P<0.01)。结论:凉血通瘀方治疗瘀热型急性脑梗死疗效显著,可以显著减轻患者梗死区域缺血情况,缩小梗死面积,降低D-二聚体水平,提高NIHSS评分和中医证候疗效。

Objective:To observe the clinical efficacy of Liangxue Tongyu Decoction in treatment of acute cerebral infarction.Methods:98 patients with acute cerebral infarction were randomly divided into control group and observation group.The control group received routine treatment,and the observation group received oral or nasal feeding of Liangxue Tongyu Recipe on the basis of the control group.After 2 weeks,the blood lipids,D-dimer,infarct size,NIHSS score and TCM syndrome efficacy were compared be?tween the two groups.Results:After treatment,the D-dimer levels in the two groups were significantly lower than those before treatment(P<0.01),and the D-dimer level in the observation group was lower than that in the control group(P<0.01).After treatment,the infarct size of the two groups was smaller than that before treatment,and the infarct size reduction rate of the observation group was better than that of the control group(P<0.01).After treatment,the NIHSS scores and TCM syndrome scores of the two groups were lower than those before treatment(P<0.01),and the observation group was lower than the control group(P<0.01).The effective rate of the control group was 73.47%,and the effective rate of the observation group was 95.92%.The effective rate of the observation group was higher than that of the control group(P<0.01).Conclusion:Liangxue Tongyu Decoction has significant curative effect on acute cerebral infarction with Phlegm-heat Syndrome,which can significantly reduce the ischemic condition of infarcted area,reduce infarct size,reduce D-dimer level,and improve NIHSS score and TCM syndrome effect.