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乌司他丁注射液联合床房持续血液净化治疗重症脓毒症 被引量:4

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摘要 目的分析乌司他丁注射液联合床房持续血液净化治疗重症脓毒症的临床效果。方法选取2014年9月至2017年9月商丘市第一人民医院收治的56例重症脓毒症患者,按入院顺序分为对照组和观察组,各28例。对照组接受床房持续血液净化治疗,观察组在此基础上加用乌司他丁注射液治疗。对比两组总有效率和IL-1β、IL-6、肿瘤坏死因子-α(TNF-α)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)水平。结果观察组总有效率(89.29%)高于对照组(64.29%),差异有统计学意义(P<0.05)。观察组治疗后IL-1β、IL-6、TNF-α水平低于对照组(均P<0.05)。观察组治疗后APTT低于对照组,FIB高于对照组(均P<0.05)。结论采用乌司他丁注射液联合床房持续血液净化治疗重症脓毒症能改善患者炎症水平,调节机体凝血功能,疗效显著。
出处 《河南医学研究》 CAS 2019年第21期3906-3908,共3页 Henan Medical Research
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  • 1Dellinger RP,Levy MM,Carlet JM,et al.Surviving sepsis campaign:international guidelines for management of severe sepsis and septic shock:2008.Crit Care Med,2008,36:296-327.
  • 2Reinhart K,Brunkhorst FM,Bone HG,et al.Prevention,diagnosis,therapy and follow-up care of sepsis,1st revision of S-2k guidelines of the German Sepsis Society[Deutsche Sepsis-Gesellschaft e.V.(DSG)] and the German Interdisciplinary Association of Intensive Care and Emergency Medicine[Deutsche Interdisziplinare Vereinigung f(u)r Intensiv-und Notfallmedizin (DIVI)].Ger Med Sci,2010,8:Doc14.
  • 3Xinliang Z,Shimin D,Yanjun Q, et al.Protective effect of erythropoietin again myocardial in rats with sepsis and its un- derlying mechanisms[J].Mol Med Rep , 2015 , 11(5):3317-3329.
  • 4Vieillard BA, Caille V,Charron C,et al .Actual incidence of global left ventricular hypokinesia in adult septic shock[J], Crit Care Med , 2008, 36(6):1701-1706.
  • 5De Groot B, Verdoorn RC, Lameijer J, et al .High-sensitivi- ty cardiac troponin T is an independent predictor of in hospital mortality in emergency department patients with suspected infection : a prospective observational derivation study [J]. Emergency Med f 2014, 31(11):882-885.
  • 6Dellinger RP, Levy MM, Rhodes A, et ai .Surviving Sepsis Campaign : International guidelines for management of severe sepsis and septic shock, 2012[J].Intensive Care Medicine,2013,39(2):165-167.
  • 7Dellinger RP, Levy MM, Rhodes A,et al .Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock, 2012[J].Intensive Care Med ?2013, 39(2):165-228.
  • 8Walkey AJ,Wiener RS.Hospital case volume and outcomes among patients hospitalized with severe sepsis[J].Am J Respir Crit Care Med,2014,189(5):548-555.
  • 9Karnad DR,Bhadade R,Verma PK,et al.Intravenous administration of ulinastatin(human urinary trypsin inhibitor)in severesepsis:a multicenter randomized controlled study[J].Intensive Care Med,2014,40(6):830-838.
  • 10Cabrera-Perez J,Condotta SA,Badovinac VP,et al.Impact of sepsis on CD4Tcell immunity[J].J Leukoc Biol,2014,96(5):767-777.

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