全身麻醉联合椎旁阻滞麻醉在肝血管瘤切除患者中的应用效果

General Anesthesia Combined with Paravertebral Block for Hepatic Hemangioma Resection

目的探讨全身麻醉联合椎旁阻滞麻醉在肝血管瘤切除患者中的应用效果。方法80例肝血管瘤患者均接受肝血管瘤切除治疗,按随机数字表法分为治疗组(n=40)和常规组(n=40)。常规组接受全身麻醉,治疗组在全身麻醉的基础上行椎旁阻滞麻醉,观察2组麻醉效果。结果治疗组术后TNF-α(血清肿瘤坏死因子α)、sTREM-1(可溶性髓样细胞触发受体)、疼痛程度(VAS评分)、疼痛不良事件发生率和舒芬太尼用量显著低于常规组(P<0.01或P<0.05)。治疗组ICU治疗、拔管、恢复进食、住院时间均显著短于常规组(均P<0.01)。结论全身麻醉联合椎旁阻滞麻醉能够显著提升肝血管瘤切除患者的麻醉效果,术后患者疼痛程度更低,并且恢复更快。

Objective To explore the efficacy of general anesthesia combined with paravertebral block for hepatic hemangioma resection.Methods Eighty patients received general anesthesia alone(routine group,n=40)or in combination with paravertebral block(treatment group,n=40)for hepatic hemangioma resection.The anesthetic efficacy was observed in both groups.Results After treatment,the levels of tumor necrosis factor-α(TNF-α)and soluble triggering receptor expressed on myeloid cells-1(sTREM-1),degree of pain(VAS score),incidence of pain-related adverse events and dosage of sufentanil in treatment group were significantly lower than those in routine group(P<0.01 or P<0.05).The duration of ICU stay,time to extubation,time to resumption of feeding and length of hospitalization in treatment group were obviously shorter than those in routine group(P<0.01).Conclusion The combination of general anesthesia and paravertebral block for hepatic hemangioma resection can improve anesthetic effect,decrease postoperative pain and promote recovery.